First install wordpress.For that follow #cd /var/www/html #vi wp-config.php Add the following line above "/* That’s all, stop editing! Happy blogging. */" /* Multisite */ define('WP_ALLOW_MULTISITE', true); Open httpd.conf and enable .htaccess file #vi /etc/httpd/conf/httpd.conf <Directory /var/www/> Options Indexes FollowSymLinks MultiViews AllowOverride All Order allow,deny allow from all </Directory> Create a directory for multisites #mkdir /var/www/html/wp-content/ blogs.dir Now restart httpd restart #service httpd restart Go to browser and login to wordpress dashboard From Tools > Network setup Select sub domain or sub directory based upon our need .Give Network title and email and cick install Now open wp-config.php file and add contents given there. Similary open .htaccess file and enter the contents given there Now login again and we have configured wordpress f